Garbhini-GA2: India-specific AI model to determine age of foetus

News Excerpt:

Researchers at the IIT Madras and Translational Health Science and Technology Institute, Faridabad have developed the first India-specific artificial intelligence (AI) model to precisely determine the age of a foetus in the second and third trimesters of pregnancy.

More about Garbhini-GA2:

  • The Garbhini-GA2 is the first late-trimester gestational age estimation model to be developed and validated using Indian population data.
    • Currently, the age of a foetus (gestational age, GA) is determined using a formula developed for Western populations and are likely to be erroneous when applied in the later part of pregnancy due to variations in the growth of the foetus in the Indian population.
  • Garbhini-GA2 accurately estimates the foetus’ age, reducing error by almost three times.
  • The research is a part of an interdisciplinary group for advanced research on birth outcomes — the DBT India initiative (GARBH-Ini) programme

Application and Importance of the model:

  • Ultrasound dating is the standard practice in early pregnancy to determine gestational age (GA).
    • However, a significant portion of women in India undergo their first ultrasound during the second or third trimester.
    • Utilizing Indian population-specific GA formulas in these cases can potentially enhance pregnancy care by providing more accurate estimates.
  • Improved accuracy in dating pregnancies can lead to better outcomes for both mothers and infants.
  • Additionally, precise dating will enhance the accuracy of epidemiological estimates for pregnancy outcomes in the country.
  • This deployment of Garbhini-GA2 will enhance the quality of care provided by obstetricians and neonatologists, ultimately contributing to the reduction of maternal and infant mortality rates in India.

Garbh-Ini:

  • Garbh-ini program was initiated by the Department of Biotechnology (DBT), in 2014 as a collaborative interdisciplinary research program.
  • This program is led by Translational Health Science and Technology Institute (THSTI), Faridabad.
  • The objective of the program is to understand both biological and non-biological factors that contribute to preterm birth (PTB).
  • It has been included as one of the Atal Jai-Anusandhan Mission Programmes by the DBT.

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