Naegleria fowleri or ‘brain-eating amoeba 

New Excerpt: 

A five-year-old girl undergoing treatment for primary amoebic meningoencephalitis (PAM), a rare infection caused by Naegleria fowleri or “brain-eating amoeba”, died at Kozhikode.

About Primary Amoebic Meningoencephalitis

  • Primary amebic meningoencephalitis (PAM) is a rare brain infection that is caused by Naegleria fowleri. 
    • It is a free-living amoeba or a single-celled living organism.
  • Naegleria fowleri is a microscopic ameba that lives in warm fresh water and soil around the world. 
    • It can infect people when it enters the body through the nose, usually while swimming. 
    • Once inside, it travels to the brain, where it destroys brain tissue and causes swelling.
  • Higher temperatures of up to 115°F (46°C) are conducive to its growth and it can survive for short periods in warm environments.
  • The amoeba can be found in warm freshwater, such as lakes and rivers, swimming pools, splash pads, surf parks, or other recreational venues that are poorly maintained or minimally chlorinated.
  • People cannot get infected with Naegleria fowleri from drinking water contaminated with the amoeba. PAM is also non-communicable.

Symptoms of Primary Amoebic Meningoencephalitis

  • The symptoms include headache, fever, nausea and vomiting. 
  • Later on, the patient may have a stiff neck and experience confusion, seizures, hallucinations and slip into a state of coma.
  • According to the US Centers for Disease Control and Prevention (CDC), 
    • Most people with PAM die within 1 to 18 days after symptoms begin. 
    • It usually leads to coma and death after 5 days.

Treatment for Primary Amoebic Meningoencephalitis

  • As earlier reported, scientists haven’t been able to identify any effective treatments for the disease yet. 
  • At present, doctors treat it with a combination of drugs, including amphotericin B, azithromycin, fluconazole, rifampin, miltefosine, and dexamethasone.

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